Hi Richard,
Thanks for writing in !
It is not recommended to manually remove the v2c file from the mentioned directory. The suggested workflow is to create a cancellation product in Sentinel EMS (in case you are an ISV), generate the license update and apply on the required machine.
For any further query, please feel free to reach us through Gemalto Support Portal https://supportportal.gemalto.com/csm/ or send an email at technical.support@gemalto.com.
Thank You,
Gaurav Bhanot